Neuropeptide Y (3-36) (human, rat)

Modify Date: 2024-01-04 19:18:05

Neuropeptide Y (3-36) (human, rat) Structure
Neuropeptide Y (3-36) (human, rat) structure
Common Name Neuropeptide Y (3-36) (human, rat)
CAS Number 150138-78-6 Molecular Weight 4011.4
Density N/A Boiling Point N/A
Molecular Formula C175H269N53O54S1 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Neuropeptide Y (3-36) (human, rat)


Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor[1][2].

 Names

Name H-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
Synonym More Synonyms

 Neuropeptide Y (3-36) (human, rat) Biological Activity

Description Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor[1][2].
Related Catalog
References

[1]. Hubers SA, et al. DPP (Dipeptidyl Peptidase)-4 Inhibition Potentiates the Vasoconstrictor Response to NPY (Neuropeptide Y) in Humans During Renin-Angiotensin-Aldosterone System Inhibition. Hypertension. 2018;72(3):712-719.

[2]. Grandt D, et al. Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul Pept. 1996;67(1):33-37.

 Chemical & Physical Properties

Molecular Formula C175H269N53O54S1
Molecular Weight 4011.4
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles3

More Articles
Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV.

Regul. Pept. 49 , 133-144, (1993)

Neuropeptide Y, peptide YY and pancreatic polypeptide share an evolutionary conserved proline-rich N-terminal sequence, a structure generally known to be inert to the attack of common proteinases, but...

Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors.

Regul. Pept. 67 , 33, (1996)

Neuropeptide Y (NPY 1-36) binds to Y1 and Y2 receptors with similar affinity. No endogenous molecular form of NPY with selectivity for Y1 or Y2 receptors has been described so far. We report the prese...

Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon.

Neurogastroenterol. Motil. 12 , 33-41, (2000)

Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and related pancreatic polypeptides were applied by superfusion and the effects upon...

 Synonyms

NEUROPEPTIDE Y (3-36) (HUMAN, RAT)