Procaspase-6 inhibitor 12
Modify Date: 2024-09-17 12:18:12
Procaspase-6 inhibitor 12 structure
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Common Name | Procaspase-6 inhibitor 12 | ||
|---|---|---|---|---|
| CAS Number | 1575392-43-6 | Molecular Weight | 296.305 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H13FN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Procaspase-6 inhibitor 12Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM.Procaspase-6 inhibitor 12 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.Procaspase-6 inhibitor 12 significantly stabilizes procaspase-6.Procaspase-6 inhibitor 12 prevents the activation of the Caspase-6 zymogen by mHTT1–586 in COS-7 cells. |
| Name | Procaspase-6 inhibitor 12 |
|---|
| Description | Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM.Procaspase-6 inhibitor 12 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.Procaspase-6 inhibitor 12 significantly stabilizes procaspase-6.Procaspase-6 inhibitor 12 prevents the activation of the Caspase-6 zymogen by mHTT1–586 in COS-7 cells. |
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| References | 1. Jeremy Murray, et al. ChemMedChem. 2014 Jan;9(1):73-7, 2. 2. Ehrnhoefer DE, et al. Cell Chem Biol. 2019 Sep 19;26(9):1295-1305.e6. |
| Molecular Formula | C16H13FN4O |
|---|---|
| Molecular Weight | 296.305 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Procaspase-6 inhibitor 12
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Procaspase-6 inhibitor 12
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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