PSB-12379

Modify Date: 2024-01-02 18:01:49

PSB-12379 Structure
PSB-12379 structure
Common Name PSB-12379
CAS Number 1802226-78-3 Molecular Weight 515.35
Density N/A Boiling Point N/A
Molecular Formula C18H23N5O9P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PSB-12379


PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).

 Names

Name PSB-12379

 PSB-12379 Biological Activity

Description PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
Related Catalog
Target

Ki: 9.03 nM (rat), 2.21 nM (human) (Ecto-5’-Nucleotidase)[1]

References

[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63.

 Chemical & Physical Properties

Molecular Formula C18H23N5O9P2
Molecular Weight 515.35
Storage condition 2-8℃
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