Methyltetrazine-PEG4-amine HCl

Modify Date: 2024-01-02 17:58:11

Methyltetrazine-PEG4-amine HCl structure	Common Name	Methyltetrazine-PEG4-amine HCl
	CAS Number	1802908-05-9	Molecular Weight	363.411
	Density	1.2±0.1 g/cm3	Boiling Point	558.7±60.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₅N₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	291.7±32.9 °C

Use of Methyltetrazine-PEG4-amine HCl

Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG4-Amine
Synonym	More Synonyms

Description	Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-[2-(2-{2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethanamine

Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-

MFCD28334553

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