Propargyl-PEG4-amine

Modify Date: 2024-01-09 22:44:51

Propargyl-PEG4-amine Structure
Propargyl-PEG4-amine structure
Common Name Propargyl-PEG4-amine
CAS Number 1013921-36-2 Molecular Weight 231.289
Density 1.0±0.1 g/cm3 Boiling Point 315.9±32.0 °C at 760 mmHg
Molecular Formula C11H21NO4 Melting Point N/A
MSDS USA Flash Point 141.3±18.8 °C

 Use of Propargyl-PEG4-amine


Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 3,6,9,12-Tetraoxapentadec-14-yn-1-amine
Synonym More Synonyms

 Propargyl-PEG4-amine Biological Activity

Description Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Banerjee SR, et al. 111In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific MembraneAntigen-Expressing Tissues. Biomacromolecules. 2017 Jan 9;18(1):201-209.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 315.9±32.0 °C at 760 mmHg
Molecular Formula C11H21NO4
Molecular Weight 231.289
Flash Point 141.3±18.8 °C
Exact Mass 231.147064
LogP -1.18
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.462

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

3,6,9,12-Tetraoxapentadec-14-yn-1-amine
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