Boc-Aminooxy-PEG2

Modify Date: 2024-01-09 11:15:39

Boc-Aminooxy-PEG2 Structure
Boc-Aminooxy-PEG2 structure
Common Name Boc-Aminooxy-PEG2
CAS Number 1807503-86-1 Molecular Weight 221.251
Density 1.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H19NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-Aminooxy-PEG2


Boc-Aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl [2-(2-hydroxyethoxy)ethoxy]carbamate
Synonym More Synonyms

 Boc-Aminooxy-PEG2 Biological Activity

Description Boc-Aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Molecular Formula C9H19NO5
Molecular Weight 221.251
Exact Mass 221.126328
LogP 0.70
Index of Refraction 1.454

 Synonyms

Carbamic acid, N-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester
MFCD28122959
2-Methyl-2-propanyl [2-(2-hydroxyethoxy)ethoxy]carbamate
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