THP-PEG9-THP

Modify Date: 2024-01-11 11:41:10

THP-PEG9-THP Structure
THP-PEG9-THP structure
Common Name THP-PEG9-THP
CAS Number 1809333-14-9 Molecular Weight 582.72
Density N/A Boiling Point N/A
Molecular Formula C28H54O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of THP-PEG9-THP


THP-PEG9-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name THP-PEG9-THP

 THP-PEG9-THP Biological Activity

Description THP-PEG9-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H54O12
Molecular Weight 582.72