Pyrene-PEG3-azide

Modify Date: 2024-01-10 23:22:49

Pyrene-PEG3-azide Structure
Pyrene-PEG3-azide structure
Common Name Pyrene-PEG3-azide
CAS Number 1817735-36-6 Molecular Weight 448.51
Density N/A Boiling Point N/A
Molecular Formula C25H28N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pyrene-PEG3-azide


Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Pyrene-amido-PEG4-azide

 Pyrene-PEG3-azide Biological Activity

Description Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H28N4O4
Molecular Weight 448.51
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