Aminooxy-PEG4-propargyl

Modify Date: 2024-01-10 11:02:02

Aminooxy-PEG4-propargyl Structure
Aminooxy-PEG4-propargyl structure
Common Name Aminooxy-PEG4-propargyl
CAS Number 1835759-78-8 Molecular Weight 247.29
Density N/A Boiling Point N/A
Molecular Formula C11H21NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG4-propargyl


Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Aminooxy-PEG4-propargyl
Synonym More Synonyms

 Aminooxy-PEG4-propargyl Biological Activity

Description Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H21NO5
Molecular Weight 247.29

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD29052160
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