t-Boc-aminooxy-PEG4-propargyl

Modify Date: 2024-01-10 23:03:31

t-Boc-aminooxy-PEG4-propargyl Structure
t-Boc-aminooxy-PEG4-propargyl structure
Common Name t-Boc-aminooxy-PEG4-propargyl
CAS Number 1895922-77-6 Molecular Weight 347.40
Density N/A Boiling Point N/A
Molecular Formula C16H29NO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-aminooxy-PEG4-propargyl


Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-aminooxy-PEG4-propargyl
Synonym More Synonyms

 t-Boc-aminooxy-PEG4-propargyl Biological Activity

Description Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C16H29NO7
Molecular Weight 347.40

 Synonyms

MFCD29764340
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