ONO 2506

Modify Date: 2024-01-09 14:06:19

ONO 2506 Structure
ONO 2506 structure
Common Name ONO 2506
CAS Number 185517-21-9 Molecular Weight 186.29100
Density 0.908 g/cm3 Boiling Point 289.3ºC at 760mmHg
Molecular Formula C11H22O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ONO 2506


Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].

 Names

Name arundic acid
Synonym More Synonyms

 ONO 2506 Biological Activity

Description Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].
Related Catalog
References

[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506:  A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.

[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.

 Chemical & Physical Properties

Density 0.908 g/cm3
Boiling Point 289.3ºC at 760mmHg
Molecular Formula C11H22O2
Molecular Weight 186.29100
Exact Mass 186.16200
PSA 37.30000
LogP 3.45770
Vapour Pressure 0.000557mmHg at 25°C
Index of Refraction 1.444

 Synthetic Route

 Synonyms

2R-propyloctanoic acid
Artocarpesin
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