1,1,1-Trifluoroethyl-PEG4-amine

Modify Date: 2024-01-14 19:52:58

1,1,1-Trifluoroethyl-PEG4-amine Structure
1,1,1-Trifluoroethyl-PEG4-amine structure
Common Name 1,1,1-Trifluoroethyl-PEG4-amine
CAS Number 1872433-72-1 Molecular Weight 275.27
Density N/A Boiling Point N/A
Molecular Formula C10H20F3NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-PEG4-amine


111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG4-amine
Synonym More Synonyms

 1,1,1-Trifluoroethyl-PEG4-amine Biological Activity

Description 111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H20F3NO4
Molecular Weight 275.27

 Synonyms

MFCD29079382