1,1,1-Trifluoroethyl-PEG5-Propargyl

Modify Date: 2024-08-14 10:03:32

1,1,1-Trifluoroethyl-PEG5-Propargyl Structure
1,1,1-Trifluoroethyl-PEG5-Propargyl structure
Common Name 1,1,1-Trifluoroethyl-PEG5-Propargyl
CAS Number 1817735-37-7 Molecular Weight 314.30
Density N/A Boiling Point N/A
Molecular Formula C13H21F3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-PEG5-Propargyl


1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG4-propargyl
Synonym More Synonyms

 1,1,1-Trifluoroethyl-PEG5-Propargyl Biological Activity

Description 1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H21F3O5
Molecular Weight 314.30

 Synonyms

MFCD29042360
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