1,1,1-Trifluoroethyl-PEG2-azide

Modify Date: 2024-01-10 11:56:19

1,1,1-Trifluoroethyl-PEG2-azide Structure
1,1,1-Trifluoroethyl-PEG2-azide structure
Common Name 1,1,1-Trifluoroethyl-PEG2-azide
CAS Number 1835759-68-6 Molecular Weight 213.16
Density N/A Boiling Point N/A
Molecular Formula C6H10F3N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-PEG2-azide


1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG2-azide

 1,1,1-Trifluoroethyl-PEG2-azide Biological Activity

Description 1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C6H10F3N3O2
Molecular Weight 213.16