1,1,1-Trifluoroethyl-PEG3-Propargyl

Modify Date: 2024-01-10 06:14:07

1,1,1-Trifluoroethyl-PEG3-Propargyl Structure
1,1,1-Trifluoroethyl-PEG3-Propargyl structure
Common Name 1,1,1-Trifluoroethyl-PEG3-Propargyl
CAS Number 1835759-73-3 Molecular Weight 226.19
Density N/A Boiling Point N/A
Molecular Formula C9H13F3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-PEG3-Propargyl


1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG2-propargyl
Synonym More Synonyms

 1,1,1-Trifluoroethyl-PEG3-Propargyl Biological Activity

Description 1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H13F3O3
Molecular Weight 226.19

 Synonyms

MFCD29052201
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