1,1,1-Trifluoroethyl-PEG4-aminooxy

Modify Date: 2024-01-10 20:58:32

1,1,1-Trifluoroethyl-PEG4-aminooxy Structure
1,1,1-Trifluoroethyl-PEG4-aminooxy structure
Common Name 1,1,1-Trifluoroethyl-PEG4-aminooxy
CAS Number 1895922-78-7 Molecular Weight 291.26
Density N/A Boiling Point N/A
Molecular Formula C10H20F3NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-PEG4-aminooxy


1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG4-aminooxy
Synonym More Synonyms

 1,1,1-Trifluoroethyl-PEG4-aminooxy Biological Activity

Description 1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H20F3NO5
Molecular Weight 291.26

 Synonyms

MFCD29764348