Amino-PEG2-t-Boc-hydrazide

Modify Date: 2024-01-16 18:52:09

Amino-PEG2-t-Boc-hydrazide Structure
Amino-PEG2-t-Boc-hydrazide structure
Common Name Amino-PEG2-t-Boc-hydrazide
CAS Number 2100306-60-1 Molecular Weight 291.34
Density N/A Boiling Point N/A
Molecular Formula C12H25N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG2-t-Boc-hydrazide


Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG2-C2-hydrazide-Boc
Synonym More Synonyms

 Amino-PEG2-t-Boc-hydrazide Biological Activity

Description Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H25N3O5
Molecular Weight 291.34

 Synonyms

MFCD30828685
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