SNIPER(AR)-51
Modify Date: 2024-01-14 16:39:27
SNIPER(AR)-51 structure
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Common Name | SNIPER(AR)-51 | ||
|---|---|---|---|---|
| CAS Number | 2113688-43-8 | Molecular Weight | 984.21 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H65N7O8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SNIPER(AR)-51SNIPER(AR)-51 (AR-51), consists of a cIAP1 ligand and an androgen ligand, connected by a linker[1]. SNIPER(AR)-51 induces androgen receptor (AR) protein degradation[1]. |
| Name | SNIPER(AR)-51 |
|---|
| Description | SNIPER(AR)-51 (AR-51), consists of a cIAP1 ligand and an androgen ligand, connected by a linker[1]. SNIPER(AR)-51 induces androgen receptor (AR) protein degradation[1]. |
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| Related Catalog | |
| In Vitro | SNIPER(AR)-51 (3 μM; 24 hours) exhibits a pronounced effect on the cell morphology of VCaP cells to induce apoptosis[1]. SNIPER(AR)-51 (3 μM; 24 hours) induces caspase-3 activation and PARP cleavage in prostate cancer VCaP cells[1]. Apoptosis Analysis[1] Cell Line: Prostate cancer VCaP cells Concentration: 3 μM Incubation Time: 24 hours Result: Induced apoptosis. Western Blot Analysis[1] Cell Line: VCaP cells Concentration: 1 μM and 3 μM Incubation Time: 24 hours Result: Induced caspase-3 activation and PARP cleavage at 3 μM. |
| References |
| Molecular Formula | C55H65N7O8S |
|---|---|
| Molecular Weight | 984.21 |