SNIPER(ABL)-062

Modify Date: 2024-01-11 11:10:04

SNIPER(ABL)-062 Structure
SNIPER(ABL)-062 structure
Common Name SNIPER(ABL)-062
CAS Number 2140260-89-3 Molecular Weight 1089.64
Density N/A Boiling Point N/A
Molecular Formula C53H63ClF2N10O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SNIPER(ABL)-062


SNIPER(ABL)-062, in which an ABL inhibitor is linked to a ligand of cIAP1 via a linker containing a variable polyethylene glycol (PEG) unit, shows a potent activity to degrade the BCR-ABL protein[1].

 Names

Name SNIPER(ABL)-062

 SNIPER(ABL)-062 Biological Activity

Description SNIPER(ABL)-062, in which an ABL inhibitor is linked to a ligand of cIAP1 via a linker containing a variable polyethylene glycol (PEG) unit, shows a potent activity to degrade the BCR-ABL protein[1].
Related Catalog
References

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

 Chemical & Physical Properties

Molecular Formula C53H63ClF2N10O9S
Molecular Weight 1089.64
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