Biotin-PEG8-amine

Modify Date: 2024-01-15 20:55:08

Biotin-PEG8-amine Structure
Biotin-PEG8-amine structure
Common Name Biotin-PEG8-amine
CAS Number 2183447-27-8 Molecular Weight 638.81
Density N/A Boiling Point N/A
Molecular Formula C28H54N4O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG8-amine


Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG8-amine
Synonym More Synonyms

 Biotin-PEG8-amine Biological Activity

Description Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

 Chemical & Physical Properties

Molecular Formula C28H54N4O10S
Molecular Weight 638.81

 Synonyms

MFCD32263742