m-PEG8-Amine structure
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Common Name | m-PEG8-Amine | ||
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CAS Number | 869718-81-0 | Molecular Weight | 383.47800 | |
Density | 1.054 | Boiling Point | 448ºC at 760 mmHg | |
Molecular Formula | C17H37NO8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 213.9ºC |
Use of m-PEG8-Aminem-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Name | 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
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Synonym | More Synonyms |
Description | m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
References |
[1]. Joshua D. Thoma, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1. |
Density | 1.054 |
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Boiling Point | 448ºC at 760 mmHg |
Molecular Formula | C17H37NO8 |
Molecular Weight | 383.47800 |
Flash Point | 213.9ºC |
Exact Mass | 383.25200 |
PSA | 99.86000 |
LogP | 0.40800 |
Storage condition | -20 °C |
Hazard Codes | Xi |
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~92% m-PEG8-Amine CAS#:869718-81-0 |
Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ; |
~90% m-PEG8-Amine CAS#:869718-81-0 |
Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ; |
Precursor 1 | |
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DownStream 0 |
3,6,9,12,15,18,21,24-OCTAOXAPENTACOSAN-1-AMINE |
AmbotzPEG1700 |