m-PEG8-bromide

Modify Date: 2024-01-21 11:44:37

m-PEG8-bromide Structure
m-PEG8-bromide structure
Common Name m-PEG8-bromide
CAS Number 1056881-04-9 Molecular Weight 447.36
Density 1.198±0.06 g/cm3(Predicted) Boiling Point 462.5±40.0 °C(Predicted)
Molecular Formula C17H35BrO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-bromide


m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG8-Br
Synonym More Synonyms

 m-PEG8-bromide Biological Activity

Description m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.198±0.06 g/cm3(Predicted)
Boiling Point 462.5±40.0 °C(Predicted)
Molecular Formula C17H35BrO8
Molecular Weight 447.36

 Synonyms

MFCD31380391
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