m-PEG8-Mal

Modify Date: 2024-01-07 12:41:56

m-PEG8-Mal Structure
m-PEG8-Mal structure
Common Name m-PEG8-Mal
CAS Number 1334169-90-2 Molecular Weight 534.597
Density 1.2±0.1 g/cm3 Boiling Point 659.0±55.0 °C at 760 mmHg
Molecular Formula C24H42N2O11 Melting Point N/A
MSDS N/A Flash Point 352.3±31.5 °C

 Use of m-PEG8-Mal


m-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide
Synonym More Synonyms

 m-PEG8-Mal Biological Activity

Description m-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 659.0±55.0 °C at 760 mmHg
Molecular Formula C24H42N2O11
Molecular Weight 534.597
Flash Point 352.3±31.5 °C
Exact Mass 534.278870
LogP -3.50
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.489

 Synonyms

1H-Pyrrole-1-propanamide, 2,5-dihydro-N-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl-2,5-dioxo-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide
Top Suppliers:I want be here




Get all suppliers and price by the below link:

m-PEG8-Mal suppliers

m-PEG8-Mal price