m-PEG8-CH2COOH

Modify Date: 2024-01-06 17:20:40

m-PEG8-CH2COOH Structure
m-PEG8-CH2COOH structure
Common Name m-PEG8-CH2COOH
CAS Number 102013-72-9 Molecular Weight 442.49800
Density 1.122 Boiling Point N/A
Molecular Formula C19H38O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-CH2COOH


m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 m-PEG8-CH2COOH Biological Activity

Description m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2.

 Chemical & Physical Properties

Density 1.122
Molecular Formula C19H38O11
Molecular Weight 442.49800
Exact Mass 442.24100
PSA 120.37000

 Safety Information

Hazard Codes Xi

 Synthetic Route

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m-PEG8-CH2COOH Structure

m-PEG8-CH2COOH

CAS#:102013-72-9

Literature: CIBA Patent: US2769838 , 1954 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

3,6,9,12,15,18,21,24,27-nonaoxa-octacosanoic acid
3,6,9,12,15,18,21,24,27-Nonaoxa-octacosansaeure
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