β-Glucuronide-dPBD-PEG5-NH2
Modify Date: 2024-01-20 10:45:53
β-Glucuronide-dPBD-PEG5-NH2 structure
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Common Name | β-Glucuronide-dPBD-PEG5-NH2 | ||
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| CAS Number | 2246363-68-6 | Molecular Weight | 1696.66 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C78H101N7O35 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of β-Glucuronide-dPBD-PEG5-NH2β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a prodrug of cIRCR201-dPBD, reduces side effects[1]. |
| Name | β-Glucuronide-dPBD-PEG5-NH2 |
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| Description | β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a prodrug of cIRCR201-dPBD, reduces side effects[1]. |
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| Related Catalog | |
| Target |
Drug-linker conjugates for ADC, Apoptosis[1] |
| References |
| Molecular Formula | C78H101N7O35 |
|---|---|
| Molecular Weight | 1696.66 |