HIV-1 inhibitor-35

Modify Date: 2024-01-10 21:49:25

HIV-1 inhibitor-35 Structure
HIV-1 inhibitor-35 structure
Common Name HIV-1 inhibitor-35
CAS Number 2416971-32-7 Molecular Weight 392.69
Density N/A Boiling Point N/A
Molecular Formula C13H12Cl3N5OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 inhibitor-35


HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent[1].

 Names

Name HIV-1 inhibitor-35

 HIV-1 inhibitor-35 Biological Activity

Description HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent[1].
Related Catalog
Target

HIV-1[1]

References

[1]. Nguyen W, et al. Optimization of 5-substituted thiazolyl ureas and 6-substituted imidazopyridines as potential HIV-1 latency reversing agents. Eur J Med Chem. 2020;195:112254.

 Chemical & Physical Properties

Molecular Formula C13H12Cl3N5OS
Molecular Weight 392.69