2416971-32-7

2416971-32-7 structure

Name: HIV-1 inhibitor-35
Chemical Name: HIV-1 inhibitor-35
CAS Number: 2416971-32-7
Molecular Formula: C₁₃H₁₂Cl₃N₅OS
Molecular Weight: 392.69
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-07-02 19:35:24
Modify Date: 2024-01-10 21:49:25
HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent[1].

Name	HIV-1 inhibitor-35

Description	HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1[1]
References	[1]. Nguyen W, et al. Optimization of 5-substituted thiazolyl ureas and 6-substituted imidazopyridines as potential HIV-1 latency reversing agents. Eur J Med Chem. 2020;195:112254.

Molecular Formula	C₁₃H₁₂Cl₃N₅OS
Molecular Weight	392.69