PROTAC BRD4 Degrader-9

Modify Date: 2024-02-05 11:18:23

PROTAC BRD4 Degrader-9 Structure
PROTAC BRD4 Degrader-9 structure
Common Name PROTAC BRD4 Degrader-9
CAS Number 2417370-42-2 Molecular Weight 1312.50
Density N/A Boiling Point N/A
Molecular Formula C59H71F2N9O15S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BRD4 Degrader-9


PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.

 Names

Name PROTAC BRD4 Degrader-9

 PROTAC BRD4 Degrader-9 Biological Activity

Description PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.

 Chemical & Physical Properties

Molecular Formula C59H71F2N9O15S4
Molecular Weight 1312.50
Storage condition 2-8°C
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