PROTAC BRD4 Degrader-13

Modify Date: 2024-08-09 20:28:20

PROTAC BRD4 Degrader-13 Structure
PROTAC BRD4 Degrader-13 structure
Common Name PROTAC BRD4 Degrader-13
CAS Number 2417370-71-7 Molecular Weight 1492.54
Density N/A Boiling Point N/A
Molecular Formula C68H85F2N11O17P2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BRD4 Degrader-13


PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively.

 Names

Name PROTAC BRD4 Degrader-13

 PROTAC BRD4 Degrader-13 Biological Activity

Description PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively.

 Chemical & Physical Properties

Molecular Formula C68H85F2N11O17P2S2
Molecular Weight 1492.54
Storage condition 2-8°C
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