CHIR-98023
Modify Date: 2024-01-10 12:39:07
CHIR-98023 structure
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Common Name | CHIR-98023 | ||
|---|---|---|---|---|
| CAS Number | 252916-76-0 | Molecular Weight | 471.29900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H16Cl2N8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CHIR-98023CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism[1][2]. |
| Name | N'-[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]-N-(5-nitropyridin-2-yl)ethane-1,2-diamine |
|---|---|
| Synonym | More Synonyms |
| Description | CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism[1][2]. |
|---|---|
| Related Catalog | |
| Target |
GSK3α:10 nM (IC50) GSK3β:6.7 nM (IC50) |
| References |
| Molecular Formula | C20H16Cl2N8O2 |
|---|---|
| Molecular Weight | 471.29900 |
| Exact Mass | 470.07700 |
| PSA | 143.69000 |
| LogP | 4.03470 |
| unii-cmq1l0e91y |
| chir-837 |