IEM 1925 dihydrobromide
Modify Date: 2024-01-15 20:50:36
IEM 1925 dihydrobromide structure
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Common Name | IEM 1925 dihydrobromide | ||
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| CAS Number | 258282-23-4 | Molecular Weight | 422.24 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H30Br2N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IEM 1925 dihydrobromideIEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy[1][2]. |
| Name | N-(1-Phenylcyclohexyl)-1,5-pentanediamine dihydrobromide |
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| Description | IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy[1][2]. |
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| Related Catalog | |
| In Vivo | IEM-1925 (10 mg/kg) 减弱了大鼠癫痫状态下的行为运动惊厥症状，将Pinel和Rovner评分中的癫痫发作强度从8分降至4分。 Animal Model: Rats (males, weight 240-350 g)[2]. Dosage: 5, 10 mg/kg. Administration: i.m. Result: Administration of 5 and 10 mg/kg IEM-1925 2 h before pilocarpine did not alter the overall SE pattern. However, IEM-1925 significantly changed the latent periods of onset and durations of the separate phases and also decreased the total duration of status. |
| References |
| Molecular Formula | C17H30Br2N2 |
|---|---|
| Molecular Weight | 422.24 |
| Exact Mass | 420.07800 |
| PSA | 38.05000 |
| LogP | 6.57200 |