S.pombe lumazine synthase-IN-1

Modify Date: 2024-01-28 11:32:28

S.pombe lumazine synthase-IN-1 Structure
S.pombe lumazine synthase-IN-1 structure
Common Name S.pombe lumazine synthase-IN-1
CAS Number 331726-35-3 Molecular Weight 319.27
Density N/A Boiling Point N/A
Molecular Formula C14H13N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S.pombe lumazine synthase-IN-1


S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1].

 Names

Name S.pombe lumazine synthase-IN-1

 S.pombe lumazine synthase-IN-1 Biological Activity

Description S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1].
Related Catalog
Target

Ki: 243 μM (Schizosaccharomyces pombe lumazine synthase); 9.6 μM (Mycobacterium tuberculosis lumazine synthase)[1]

In Vitro S.pombe lumazine synthase-IN-1 (Compound 21) is a class II compound with OCH3 groups displays slightly better potencies than its counterparts with OH groups[1].
References

[1]. Arindam Talukdar, et al. Discovery and Development of a Small Molecule Library With Lumazine Synthase Inhibitory Activity. J Org Chem. 2009 Aug 7;74(15):5123-34.

 Chemical & Physical Properties

Molecular Formula C14H13N3O6
Molecular Weight 319.27
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