331726-35-3

331726-35-3 structure

Name: S.pombe lumazine synthase-IN-1
Chemical Name: S.pombe lumazine synthase-IN-1
CAS Number: 331726-35-3
Molecular Formula: C₁₄H₁₃N₃O₆
Molecular Weight: 319.27
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2020-08-10 23:41:29
Modify Date: 2024-01-28 11:32:28
S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1].

Name	S.pombe lumazine synthase-IN-1

Description	S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
Target	Ki: 243 μM (Schizosaccharomyces pombe lumazine synthase); 9.6 μM (Mycobacterium tuberculosis lumazine synthase)[1]
In Vitro	S.pombe lumazine synthase-IN-1 (Compound 21) is a class II compound with OCH3 groups displays slightly better potencies than its counterparts with OH groups[1].
References	[1]. Arindam Talukdar, et al. Discovery and Development of a Small Molecule Library With Lumazine Synthase Inhibitory Activity. J Org Chem. 2009 Aug 7;74(15):5123-34.

Molecular Formula	C₁₄H₁₃N₃O₆
Molecular Weight	319.27