Mal-PEG2-alcohol structure
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Common Name | Mal-PEG2-alcohol | ||
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CAS Number | 34321-81-8 | Molecular Weight | 185.17700 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C8H11NO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Mal-PEG2-alcoholMal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 1-[2-(2-hydroxyethoxy)ethyl]pyrrole-2,5-dione |
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Synonym | More Synonyms |
Description | Mal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C8H11NO4 |
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Molecular Weight | 185.17700 |
Exact Mass | 185.06900 |
PSA | 66.84000 |
~92% Mal-PEG2-alcohol CAS#:34321-81-8 |
Literature: Heredia, Karina L.; Bontempo, Debora; Ly, Tiffany; Byers, Joshua T.; Halstenberg, Sven; Maynard, Heather D. Journal of the American Chemical Society, 2005 , vol. 127, # 48 p. 16955 - 16960 |
~% Mal-PEG2-alcohol CAS#:34321-81-8 |
Literature: Raouane, Mouna; Desmaele, Didier; Gilbert-Sirieix, Marie; Gueutin, Claire; Zouhiri, Fatima; Bourgaux, Claudie; Lepeltier, Elise; Gref, Ruxandra; Ben Salah, Ridha; Clayman, Gary; Massaad-Massade, Liliane; Couvreur, Patrick Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4067 - 4076 |
Precursor 3 | |
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DownStream 0 |
MFCD16780862 |