m-PEG9-CH2COOH

Modify Date: 2024-01-02 16:26:09

m-PEG9-CH2COOH Structure
m-PEG9-CH2COOH structure
Common Name m-PEG9-CH2COOH
CAS Number 405518-55-0 Molecular Weight 486.55100
Density 1.122 Boiling Point 557.372ºC at 760 mmHg
Molecular Formula C21H42O12 Melting Point N/A
MSDS N/A Flash Point 175.904ºC

 Use of m-PEG9-CH2COOH


m-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 m-PEG9-CH2COOH Biological Activity

Description m-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.122
Boiling Point 557.372ºC at 760 mmHg
Molecular Formula C21H42O12
Molecular Weight 486.55100
Flash Point 175.904ºC
Exact Mass 486.26800
PSA 129.60000

 Synonyms

2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontan-31-oic acid
3,6,9,12,15,18,21,24,27,30-DECAOXAHENTRIACONTANOIC ACID