m-PEG9-SH

Modify Date: 2024-01-03 20:24:56

m-PEG9-SH Structure
m-PEG9-SH structure
Common Name m-PEG9-SH
CAS Number 651042-84-1 Molecular Weight 444.58100
Density 1.075 Boiling Point N/A
Molecular Formula C19H40O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG9-SH


m-PEG9-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG9-SH Biological Activity

Description m-PEG9-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.075
Molecular Formula C19H40O9S
Molecular Weight 444.58100
Exact Mass 444.23900
PSA 121.87000
LogP 0.69540
Storage condition 2-8°C

 Synonyms

2,5,8,11,14,17,20,23,26-nonaoxaoctacosane-28-thiol
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