5,7,3',4',5'-Pentamethoxyflavone

Modify Date: 2024-01-04 17:00:08

5,7,3',4',5'-Pentamethoxyflavone Structure
5,7,3',4',5'-Pentamethoxyflavone structure
Common Name 5,7,3',4',5'-Pentamethoxyflavone
CAS Number 53350-26-8 Molecular Weight 372.36900
Density 1.244g/cm3 Boiling Point 554.4ºC at 760mmHg
Molecular Formula C20H20O7 Melting Point 198-200ºC
MSDS N/A Flash Point 243.5ºC

 Use of 5,7,3',4',5'-Pentamethoxyflavone


3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1].

 Names

Name 3',4',5',5,7-Pentamethoxyflavone
Synonym More Synonyms

 5,7,3',4',5'-Pentamethoxyflavone Biological Activity

Description 3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway[1].
Related Catalog
References

[1]. Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401.

 Chemical & Physical Properties

Density 1.244g/cm3
Boiling Point 554.4ºC at 760mmHg
Melting Point 198-200ºC
Molecular Formula C20H20O7
Molecular Weight 372.36900
Flash Point 243.5ºC
Exact Mass 372.12100
PSA 76.36000
LogP 3.50300
Index of Refraction 1.565
Storage condition 2-8°C

 Safety Information

Safety Phrases S22-S24/25
HS Code 2914509090

 Synthetic Route

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
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