N-Succinimidyl 3-maleimidopropionate

Modify Date: 2024-01-09 17:18:55

N-Succinimidyl 3-maleimidopropionate structure	Common Name	N-Succinimidyl 3-maleimidopropionate
	CAS Number	55750-62-4	Molecular Weight	266.20700
	Density	1.55g/cm3	Boiling Point	448.8ºC at 760mmHg
	Molecular Formula	C₁₁H₁₀N₂O₆	Melting Point	168-170 °C(lit.)
	MSDS	Chinese USA	Flash Point	225.2ºC
	Symbol	GHS07	Signal Word	Warning

Use of N-Succinimidyl 3-maleimidopropionate

BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name	N-Succinimidyl 3-maleimidopropionate
Synonym	More Synonyms

Description	BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Noncleavable

Density	1.55g/cm3
Boiling Point	448.8ºC at 760mmHg
Melting Point	168-170 °C(lit.)
Molecular Formula	C₁₁H₁₀N₂O₆
Molecular Weight	266.20700
Flash Point	225.2ºC
Exact Mass	266.05400
PSA	101.06000
Index of Refraction	1.605
Storage condition	2-8°C

N-Succinimidyl 3-maleimidopropionate MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H335
Precautionary Statements	P261
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R37
Safety Phrases	S26-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2925190090

Maleic anhydride

CAS#:108-31-6

N-Hydroxysuccinimide

CAS#:6066-82-6

beta-Alanine

CAS#:107-95-9

~80%

N-Succinimidyl ...

CAS#:55750-62-4

Literature: CYTOS BIOTECHNOLOGY AG; WOOD, Andrew; SMITH, Helen, Kathryn; WILMSHURST, Martin, Philip; VAN, Son Thanh Patent: WO2011/23680 A2, 2011 ; Location in patent: Page/Page column 13-14 ;

N-Hydroxysuccinimide

CAS#:6066-82-6

3-Maleimidoprop...

CAS#:7423-55-4

N-Succinimidyl ...

CAS#:55750-62-4

Literature: Tetrahedron Letters, , vol. 39, # 11 p. 1321 - 1324

Sodium bisulfate

CAS#:7681-38-1

TSTU

CAS#:105832-38-0

N,N-Dimethylfor...

CAS#:68-12-2

N-Succinimidyl ...

CAS#:55750-62-4

Literature: US2012/93840 A1, ;

N-Succinimidyl ...

CAS#:5672-89-9

CIS-5-AZA-4-OXO...

CAS#:57079-11-5

~66%

N-Succinimidyl ...

CAS#:55750-62-4

Literature: Paterson, Michael J.; Eggleston, Ian M. Synthetic Communications, 2008 , vol. 38, # 2 p. 303 - 308

3-Maleimidoprop...

CAS#:7423-55-4

Dicyclohexylcar...

CAS#:538-75-0

N-Succinimidyl ...

CAS#:55750-62-4

Urea

CAS#:57-13-6

Literature: Song, Hong Y.; Ngai, Mun H.; Song, Zhen Y.; MacAry, Paul A.; Hobley, Jonathan; Lear, Martin J. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 17 p. 3400 - 3406

N-Hydroxysuccinimide

CAS#:6066-82-6

CIS-5-AZA-4-OXO...

CAS#:57079-11-5

~48%

N-Succinimidyl ...

CAS#:55750-62-4

Literature: Augustin, Manfred; Mueller, Wolfgang Journal fuer Praktische Chemie (Leipzig), 1985 , vol. 327, # 5 p. 789 - 798

CIS-5-AZA-4-OXO...

CAS#:57079-11-5

N-Succinimidyl ...

CAS#:55750-62-4

Literature: Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6400 - 6407

Precursor 10
CAS#:108-31-6 Maleic anhydride CAS#:6066-82-6 N-Hydroxysuccinimide CAS#:107-95-9 beta-Alanine CAS#:7423-55-4 3-Maleimidoprop...
CAS#:7681-38-1 Sodium bisulfate CAS#:105832-38-0 TSTU CAS#:68-12-2 N,N-Dimethylfor... CAS#:5672-89-9 N-Succinimidyl ...
CAS#:57079-11-5 CIS-5-AZA-4-OXO... CAS#:538-75-0 Dicyclohexylcar...
DownStream 1
CAS#:367927-39-7 SMPH Crosslinker

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Nanobody-functionalized PEG-b-PCL polymersomes and their targeting study.

J. Biotechnol. 214 , 147-55, (2015)

We prepared and characterized polymersomes functionalized with nanobodies (VHHs) on the basis of biocompatible, biodegradable and FDA-approved poly(ethylene glycol)-block-poly(ϵ-caprolactone) (PEG-b-P...

Immobilization of the cell-adhesive peptide Arg-Gly-Asp-Cys (RGDC) on titanium surfaces by covalent chemical attachment.

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Covalent attachment of functionalized lipid bilayers to planar waveguides for measuring protein binding to biomimetic membranes.

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A new method is presented for measuring sensitively the interactions between ligands and their membrane-bound receptors in situ using integrated optics, thus avoiding the need for additional labels. P...

1-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione

(2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate

1-{3-[(2,5-Dioxopyrrolidin-1-yl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione

MFCD00043141

1H-pyrrole-2,5-dione, 1-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-