FEN1-IN-C20

Modify Date: 2023-10-16 17:09:24

FEN1-IN-C20 structure	Common Name	FEN1-IN-C20
	CAS Number	824983-94-0	Molecular Weight	393.417
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₅N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FEN1-IN-C20

FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM; significantly suppresses cell proliferation and induces DNA damage in lung cancer cells, enhances the therapeutic effect of cisplatin; efficiently suppresses cancer progression in combination with cisplatin in mouse models.

Name	FEN1-IN-C20

Description	FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM; significantly suppresses cell proliferation and induces DNA damage in lung cancer cells, enhances the therapeutic effect of cisplatin; efficiently suppresses cancer progression in combination with cisplatin in mouse models.
References	References 1. Exell JC, et al. Nat Chem Biol. 2016 Oct;12(10):815-21. 2. He L, et al. Mol Oncol. 2017 Jun;11(6):640-654. 3. He L, et al. EBioMedicine. 2016 Dec;14:32-43. View Related Products by Target Other Targets

Molecular Formula	C₂₀H₁₅N₃O₄S
Molecular Weight	393.417

DC Chemicals Limited
China
Product Name: FEN1-IN-C20
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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