Benzyl-PEG5-azide

Modify Date: 2024-01-09 12:09:47

Benzyl-PEG5-azide Structure
Benzyl-PEG5-azide structure
Common Name Benzyl-PEG5-azide
CAS Number 86770-72-1 Molecular Weight 353.413
Density N/A Boiling Point N/A
Molecular Formula C17H27N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG5-azide


Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 16-Azido-1-phenyl-2,5,8,11,14-pentaoxahexadecane
Synonym More Synonyms

 Benzyl-PEG5-azide Biological Activity

Description Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H27N3O5
Molecular Weight 353.413
Exact Mass 353.195068
LogP 0.82

 Synonyms

16-Azido-1-phenyl-2,5,8,11,14-pentaoxahexadecane
2,5,8,11,14-Pentaoxahexadecane, 16-azido-1-phenyl-
Benzyl-PEG5-azide
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