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86770-77-6

86770-77-6 structure
86770-77-6 structure
  • Name: Benzyl-PEG5-amine
  • Chemical Name: Benzyl-PEG5-Amine
  • CAS Number: 86770-77-6
  • Molecular Formula: C17H29NO5
  • Molecular Weight: 327.416
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-03 13:20:01
  • Modify Date: 2024-01-14 08:51:27
  • Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Benzyl-PEG5-Amine
Synonyms 2,5,8,11,14-Pentaoxahexadecan-16-amine, 1-phenyl-
MFCD28976656
1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-amine
Description Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 429.7±40.0 °C at 760 mmHg
Molecular Formula C17H29NO5
Molecular Weight 327.416
Flash Point 210.7±21.0 °C
Exact Mass 327.204559
LogP -0.03
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.498