230620-74-3
230620-74-3 structure
- Name: Benzyl-PEG5-THP
- Chemical Name: 2-[(1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl)oxy]tetrahydro-2H-pyran
- CAS Number: 230620-74-3
- Molecular Formula: C22H36O7
- Molecular Weight: 412.517
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-06 01:53:36
- Modify Date: 2024-01-09 18:40:35
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Benzyl-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[(1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl)oxy]tetrahydro-2H-pyran |
|---|---|
| Synonyms |
MFCD29049394
2-[(1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl)oxy]tetrahydro-2H-pyran 2H-Pyran, tetrahydro-2-[(16-phenyl-3,6,9,12,15-pentaoxahexadec-1-yl)oxy]- |
| Description | Benzyl-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 506.0±50.0 °C at 760 mmHg |
| Molecular Formula | C22H36O7 |
| Molecular Weight | 412.517 |
| Flash Point | 197.3±30.0 °C |
| Exact Mass | 412.246094 |
| LogP | 0.59 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.502 |