GPi 688
Modify Date: 2024-01-11 17:38:33
GPi 688 structure
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Common Name | GPi 688 | ||
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| CAS Number | 918902-32-6 | Molecular Weight | 419.88 | |
| Density | 1.59±0.1 g/cm3 (20 °C, 760 mmHg) | Boiling Point | 885.9±65.0 °C (760 mmHg) | |
| Molecular Formula | C19H18ClN3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GPi 688GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC50s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively[1]. GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia[2]. |
| Name | 6H-Thieno[2,3-b]pyrrole-5-carboxamide, 2-chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl] |
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| Synonym | More Synonyms |
| Description | GPi688 is a potent and orally active glycogen phosphorylase (GPa) inhibitor with IC50s of 19 nM, 61 nM and 12 nM for human liver GPa, rat liver GPa and human skeletal muscle GPa, respectively[1]. GPi688 can inhibit glucagons-mediated glucose output in rat primary hepatocytes. GPi688 can be used for researching glucagon-mediated hyperglycaemia[2]. |
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| Related Catalog | |
| Target |
IC50: 19 nM (human liver GPa), 61 nM (rat liver GPa), 12 nM (human skeletal muscle GPa)[1] |
| References |
| Density | 1.59±0.1 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 885.9±65.0 °C (760 mmHg) |
| Molecular Formula | C19H18ClN3O4S |
| Molecular Weight | 419.88 |
| Exact Mass | 419.07100 |
| PSA | 133.90000 |
| LogP | 2.37960 |
| GPi 688 |