ADAMTS-5 Inhibitor
Modify Date: 2024-01-28 16:38:56
ADAMTS-5 Inhibitor structure
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Common Name | ADAMTS-5 Inhibitor | ||
|---|---|---|---|---|
| CAS Number | 929634-33-3 | Molecular Weight | 449.92100 | |
| Density | 1.59±0.1 g/cm3 (20 °C, 760 mmHg) | Boiling Point | N/A | |
| Molecular Formula | C16H11ClF3N3OS3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ADAMTS-5 InhibitorADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1]. |
| Name | 4-Thiazolidinone, 5-[[5-[[(4-chlorophenyl)methyl]thio]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene]-2-thioxo |
|---|---|
| Synonym | More Synonyms |
| Description | ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ADAMTS-5 (aggrecanase-2) is an extracellular matrix-degrading protease implicated in cartilage destruction in arthritis[2]. |
| References |
| Density | 1.59±0.1 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Molecular Formula | C16H11ClF3N3OS3 |
| Molecular Weight | 449.92100 |
| Exact Mass | 448.97000 |
| PSA | 129.61000 |
| LogP | 5.20220 |
| Storage condition | -20°C |
| adamts-5 inhibitor |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: ADAMTS-5 Inhibitor
- Price: Negotiable
- Purity: 99.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Adamts-5 Inhibitor
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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Price: ￥2750/10 mM * 1 mL in DMSO
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