Propargyl-PEG2-amine
Modify Date: 2024-01-03 19:05:46
Propargyl-PEG2-amine structure
|
Common Name | Propargyl-PEG2-amine | ||
|---|---|---|---|---|
| CAS Number | 944561-44-8 | Molecular Weight | 143.18400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H13NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Propargyl-PEG2-aminePropargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2]. |
| Name | 2-(2-(prop-2-yn-1-yloxy)ethoxy)ethan-1-amine |
|---|---|
| Synonym | More Synonyms |
| Description | Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable PEGs |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[2]. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1. |
| Molecular Formula | C7H13NO2 |
|---|---|
| Molecular Weight | 143.18400 |
| Exact Mass | 143.09500 |
| PSA | 44.48000 |
| LogP | 0.31180 |
| Storage condition | 2-8°C |
| RIDADR | 2735.0 |
|---|---|
| Hazard Class | 8.0 |
| 2-(2-(prop-2-yn-1-yloxy)ethoxy)ethanamine |
| 2-(2-(prop-2-ynyloxy)ethoxy)ethanamine |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Propargyl-PEG2-amine
- Price: Click To Check
- Purity: 97.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Propargyl-PEG2-amine
- Price: ￥1328.0/1g
- Purity: 98.0%
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- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Propargyl-PEG2-amine
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Propargyl-PEG2-amine
- Price: $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-[2-(2-Propynyloxy)ethoxy]ethylamine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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