DNA Gyrase-IN-4

Modify Date: 2024-01-10 10:02:37

DNA Gyrase-IN-4 structure	Common Name	DNA Gyrase-IN-4
	CAS Number	2416400-32-1	Molecular Weight	460.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₅Cl₂NO₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DNA Gyrase-IN-4

DNA Gyrase-IN-4 (compound 8p) is a potent DNA gyrase inhibitor, with an IC50 of 0.13 μM. DNA Gyrase-IN-4 shows excellent antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella and Escherichia coli, with MIC values of 0.05, 0.05, 0.05, and 8 μg/mL, respectively[1].

Name	DNA Gyrase-IN-4

Description	DNA Gyrase-IN-4 (compound 8p) is a potent DNA gyrase inhibitor, with an IC50 of 0.13 μM. DNA Gyrase-IN-4 shows excellent antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella and Escherichia coli, with MIC values of 0.05, 0.05, 0.05, and 8 μg/mL, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 0.13 μM (DNA gyrase)[1]
References	[1]. Liu H, et al. Novel coumarin-thiazolyl ester derivatives as potential DNA gyrase Inhibitors: Design, synthesis, and antibacterial activity. Bioorg Chem. 2020 Jul;100:103907.

Molecular Formula	C₂₂H₁₅Cl₂NO₄S
Molecular Weight	460.33

DNA Gyrase-IN-4

Use of DNA Gyrase-IN-4

Names

DNA Gyrase-IN-4 Biological Activity

Chemical & Physical Properties