TREM2 agonist-1

Modify Date: 2024-06-08 17:58:12

TREM2 agonist-1 structure	Common Name	TREM2 agonist-1
	CAS Number	2738486-70-7	Molecular Weight	437.90
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁ClFN₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TREM2 agonist-1

TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].

Name	TREM2 agonist-1

Description	TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	TREM2 agonist-1 (0-100 μM; 16 h) treatment activates hTREM2 in HEK293 cell[1]. Cell Viability Assay[1] Cell Line: HEK293 cells Concentration: 0-100 μM Incubation Time: 16 hours Result: Showed an EC50 value between 3.0 μM and 100 μM.
References	[1]. Lara C. CZABANIUK, et al. Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use. WO2021226629A1.

Molecular Formula	C₂₃H₂₁ClFN₅O
Molecular Weight	437.90