SARS-CoV-2-IN-35

Modify Date: 2024-01-16 19:35:10

SARS-CoV-2-IN-35 Structure
SARS-CoV-2-IN-35 structure
Common Name SARS-CoV-2-IN-35
CAS Number 2757763-47-4 Molecular Weight 621.67
Density N/A Boiling Point N/A
Molecular Formula C29H34F3N5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2-IN-35


SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].

 Names

Name SARS-CoV-2-IN-35

 SARS-CoV-2-IN-35 Biological Activity

Description SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].
Related Catalog
In Vivo SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats[1]. Animal Model: Wistar-Han rats[1] Dosage: 10 mg/kg Administration: Oral administration Result: Had oral F of 33 %.
References

[1]. Owen DR, et, al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science. 2021 Dec 24;374(6575):1586-1593.  

 Chemical & Physical Properties

Molecular Formula C29H34F3N5O5S
Molecular Weight 621.67