GID4 Ligand 3

Modify Date: 2024-01-12 17:12:09

GID4 Ligand 3 structure	Common Name	GID4 Ligand 3
	CAS Number	340007-39-8	Molecular Weight	208.280
	Density	1.3±0.1 g/cm3	Boiling Point	366.5±44.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₂N₂OS	Melting Point	N/A
	MSDS	N/A	Flash Point	175.4±28.4 °C

Use of GID4 Ligand 3

GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC50 value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau[1].

Name	3-[(5-Methyl-4,5-dihydro-1,3-thiazol-2-yl)amino]phenol
Synonym	More Synonyms

Description	GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC50 value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 148.5 μM (GID4)[1]
In Vitro	GID4 Ligand 3 (0-1000 μM; 30 min) binds with GID4 with a Kd value of 110 μM[1].
References	[1]. Chana CK, et al. Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem. 2022 Sep 18.

Density	1.3±0.1 g/cm3
Boiling Point	366.5±44.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂N₂OS
Molecular Weight	208.280
Flash Point	175.4±28.4 °C
Exact Mass	208.067032
LogP	1.20
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.663

3-[(5-Methyl-4,5-dihydro-1,3-thiazol-2-yl)amino]phenol

Phenol, 3-[(4,5-dihydro-5-methyl-2-thiazolyl)amino]-

MFCD01655227

GID4 Ligand 3

Use of GID4 Ligand 3

Names

GID4 Ligand 3 Biological Activity

Chemical & Physical Properties

Synonyms