HDAC6/8/BRPF1-IN-1 structure
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Common Name | HDAC6/8/BRPF1-IN-1 | ||
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CAS Number | 2484255-65-2 | Molecular Weight | 387.41 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H17N3O5S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HDAC6/8/BRPF1-IN-1HDAC6/8/BRPF1-IN-1 is a dual inhibitor of both HDAC6/8 and the bromodomain and PHD finger containing protein 1 (BRPF1). HDAC6/8/BRPF1-IN-1 has inhibitory activity for HDAC1, HDAC6 and HDAC8 with IC50 values of 797 nM, 344 nM and 908 nM, respectively. HDAC6/8/BRPF1-IN-1 has inhibitory activity for BRPF1 with an Kd value of 175.2 nM. HDAC6/8/BRPF1-IN-1 can be used for the research of cancer[1]. |
Name | HDAC6/8/BRPF1-IN-1 |
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Description | HDAC6/8/BRPF1-IN-1 is a dual inhibitor of both HDAC6/8 and the bromodomain and PHD finger containing protein 1 (BRPF1). HDAC6/8/BRPF1-IN-1 has inhibitory activity for HDAC1, HDAC6 and HDAC8 with IC50 values of 797 nM, 344 nM and 908 nM, respectively. HDAC6/8/BRPF1-IN-1 has inhibitory activity for BRPF1 with an Kd value of 175.2 nM. HDAC6/8/BRPF1-IN-1 can be used for the research of cancer[1]. |
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Related Catalog | |
Target |
HDAC1:797 nM (IC50) HDAC6:344 nM (IC50) HDAC8:908 nM (IC50) |
In Vitro | HDAC6/8/BRPF1-IN-1 has inhibitory activity for HDAC1, HDAC6 and HDAC8 with IC50 values of 797 nM, 344 nM and 908 nM, respectively[1]. HDAC6/8/BRPF1-IN-1 has inhibitory activity for BRPF1 with an Kd value of 175.2 nM[1]. |
References |
Molecular Formula | C18H17N3O5S |
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Molecular Weight | 387.41 |